|Manufacturer:||Schering-Plough manufactures Ovestin.|
|Uses:||The uses of Ovestin include:|
Atrophy of the lower urogenital tract related to oestrogen deficiency, notably
1.For the treatment of vaginal complaints such as dyspareunia, dryness and itching.
for the prevention of recurrent infections of the vagina and lower urinary tract.
2.In the management of micturition complaints (such as frequency and dysuria) and mild urinary incontinence.
Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery.
3.Climacteric complaints such as hot flushes and night sweating.
4.A diagnostic aid in case of a doubtful atrophic cervical smear.
5.Infertility due to cervical hostility.
Dosage And Administration:
Atrophy of the lower urogenital tract:
4-8mg per day for the first weeks, followed by a gradual reduction, based on relief of symptoms, until a maintenance dosage (e.g. 1-2mg per day) is reached.
Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery:
4-8mg per day in the 2 weeks before surgery; 1-2mg per day in the 2 weeks after surgery.
Climacteric complaints such as hot flushes and night sweating:
4-8mg per day during the first weeks, followed by a gradual reduction. The lowest effective dosage should be used. In case of long-term treatment in women with an intact uterus, monitoring of the endometrium or, alternatively, concomitant use of a progestagen is recommended
A diagnostic aid in case of a doubtful atrophic cervical smear
2-4mg per day for 7 days before taking the next smear.
Infertility due to cervical hostility
In general 1-2mg per day on days 6-15 of the menstrual cycle. However, for some patients dosages as low as 1mg per day are sufficient, whereas others may need up to 8mg per day. Therefore, the dosage should be increased each month until an optimal effect on the cervical mucus is obtained.
A missed dose should be taken as soon as remembered, unless it is more than 12 hours overdue. In the latter case the missed dose should be skipped and the next dose should be taken at the normal time. The tablets should be swallowed with some water or other drink, preferably at the same time every day. It is important that the total daily dose is taken at one time.
For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration of time should be used (see also Warnings and Precautions).
In women not taking HRT or women who switch from a continuous combined HRT product, treatment with OVESTIN may be started on any day. Women who switch from cyclic HRT regimen should start OVESTIN treatment one week after completion of the cycle.