|Manufacturer:||GlaxoSmithKline manufactures Augmentin.|
|Uses:||The uses of Augmentin include:|
AUGMENTIN is indicated for the short term treatment of common bacterial infections such as:
Upper Respiratory Tract Infections (including ENT): e.g. tonsillitis, sinusitis, otitis media
Lower Respiratory Tract Infections: e.g. acute exacerbations of chronic bronchitis, lobar and broncho-pneumonia
Genito-urinary Tract Infections: e.g. cystitis, urethritis, pyelonephritis, female genital infections
Skin and Soft Tissue Infections
Bone and Joint Infections: e.g. osteomyelitis
Other Infections: e.g. septic abortion, puerperal sepsis, intra-abdominal sepsis, septicaemia, peritonitis, post-surgical infections
AUGMENTIN is indicated for prophylaxis against infection which may be associated with major surgical procedures such as gastro-intestinal, pelvic, head and neck, cardiac, renal, joint replacement and biliary tract surgery.
Infections caused by amoxicillin susceptible organisms are amenable to AUGMENTIN treatment due to its amoxicillin content. Mixed infections caused by amoxicillin susceptible organism in conjunction with AUGMENTIN-susceptible beta-lactamase-producing organisms may therefore be treated by AUGMENTIN.
Premature: No dosage recommendations can be made for this category.
Children 3-9 months: 1.25mL of AUGMENTIN Syrup 125 three times a day.
Children 9 months - 2 years: 2.5mL of AUGMENTIN Syrup 125 three times a day.
Children 2-6 years: 5mL of AUGMENTIN Syrup 125 three times a day. In severe infections this may be increased to 10mL AUGMENTIN Syrup 125 three times a day.
Children 7-12 years: 5mL of AUGMENTIN Syrup 250 three times daily. In severe infections this may be increased to 10mL of AUGMENTIN Syrup 250 three times a day.
Adults and Children 40kg and over: 1 AUGMENTIN 500 Tablet twice daily for mild to moderate infections. For lower respiratory tract infections, complicated urinary tract infections or severe infections at other sites, 1-2 AUGMENTIN 500 Tablet three times daily.
Dosage for surgical prophylaxis: Surgical prophylaxis with AUGMENTIN should aim to protect the patient for the period of risk of infection. Accordingly, procedures in adults lasting for less than 1 hour are successfully covered by 1.2g AUGMENTIN Intravenous given at induction of anaesthesia. Longer operations require subsequent doses of 1.2g AUGMENTIN IV (up to 4 doses in 24 hours), and this regime can be continued for several days if the procedure has significantly increased the risk of infection. Clear clinical signs of infection at operation will require a normal course of IV or oral AUGMENTIN therapy post-operatively.
Dosage in hepatic impairment: Dose with caution; monitor hepatic function at regular intervals for both adults and children.
There are as yet insufficient data on which to base a dosage recommendation.
Dosage in elderly: No adjustment needed, dose as for adults. If there is evidence of renal impairment, dose should be adjusted as for renally impaired adults
In patients with a history of hypersensitivity to beta-lactams, e.g. penicillins and cephalosporins.
AUGMENTIN is contraindicated in patients with a previous history of AUGMENTIN-associated jaundice/hepatic dysfunction.